Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.The collection of fossils within sedimentary rocks give a record of common ancestry and often depicts the history of evolution.
Detection of Black Holes01:10

Detection of Black Holes

Although black holes were theoretically postulated in the 1920s, they remained outside the domain of observational astronomy until the 1970s.
Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light.
Not until the 1960s, when the first neutron...
Eyewitness Memory01:22

Eyewitness Memory

Eyewitness memory refers to the recollection of events by someone who has directly witnessed them, often serving as critical evidence in legal settings. This type of memory is commonly used in criminal cases where a witness describes details like a suspect's appearance, clothing, or behavior during a crime. However, despite its perceived reliability, eyewitness memory is prone to significant errors.
One such error is memory distortion, which occurs because human memory does not function like a...
Confirmation Biases01:31

Confirmation Biases

The confirmation bias is the tendency to focus on information that confirms our existing beliefs and ignore information that is inconsistent with our expectations. For example, if you think that your professor is not very nice, you notice all of the instances of rude behavior exhibited by the professor while ignoring the countless pleasant interactions he is involved in on a daily basis. Have you ever fallen prey to the confirmation bias, either as the source or target of such bias?
What is Evolutionary History?02:35

What is Evolutionary History?

Scientists record evolutionary history by analyzing fossil, morphological, and genetic data. The fossil record documents the history of life on Earth and provides evidence for evolution. However, both fossil and living organisms offer evidence that outlines Earth’s evolutionary history.Phylogenetic trees illustrate the evolutionary relationships among these organisms. Scientists infer organisms’ common ancestry by evaluating shared morphological and genetic characteristics. Together, the fossil...
Social Proof00:52

Social Proof

Social proof is a form of persuasion based on comparison and conformity. People compare their behavior and actions to what others are doing and will change to conform to do what their peers do.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gene x environment interaction analysis confirms genetic modifier effects on steroid efficacy via TGF-β pathway in Duchenne muscular dystrophy.

European journal of human genetics : EJHG·2026
Same author

The effect of ascertainment on penetrance estimates for rare variants: Implications for establishing pathogenicity and for genetic counselling.

PloS one·2023
Same author

A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severity.

European journal of human genetics : EJHG·2023
Same author

The PPLD has advantages over conventional regression methods in application to moderately sized genome-wide association studies.

PloS one·2021
Same author

Segregating patterns of copy number variations in extended autism spectrum disorder (ASD) pedigrees.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2020
Same author

A new linear regression-like residual for survival analysis, with application to genome wide association studies of time-to-event data.

PloS one·2020
Same journal

Comparative profiles of pediatric Mendeliome: A Single-Centre 572-Whole-Exome Sequencing Study in Xinjiang.

Human heredity·2026
Same journal

Erratum.

Human heredity·2026
Same journal

Exploratory Analysis of HMGB1 Genetic Variants and Their Potential Association with Lung Cancer Susceptibility and Chemotherapy Response in a Chinese Population.

Human heredity·2025
Same journal

Weighted Burden Analysis of Rare Genetic Variants Identifies Novel Genes with Effects on BMI.

Human heredity·2025
Same journal

Generalized Stable Population and Agent-Based Models of Phenotypic Transmission in Human Populations, with an Application to Body Size.

Human heredity·2025
Same journal

Proteinase-activated receptor 2 (PAR-2) expression and F2RL1 genetic variants are associated with asthma: a case-control study in the Chinese population.

Human heredity·2025
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Evidence for EpCAM and Cytokeratin Expressing Epithelial Cells in Normal Human and Murine Blood and Bone Marrow
08:02

Evidence for EpCAM and Cytokeratin Expressing Epithelial Cells in Normal Human and Murine Blood and Bone Marrow

Published on: April 21, 2023

Where's the evidence?

Veronica J Vieland1

  • 1Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205, USA. Veronica.Vieland@NationwideChildrens.org

Human Heredity
|March 23, 2011
PubMed
Summary
This summary is machine-generated.

Statistical evidence measurement lacks a fixed scale, hindering scientific rigor. This study proposes using thermodynamics principles to develop an absolute scale for measuring statistical evidence, improving research reliability.

More Related Videos

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm
09:49

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm

Published on: December 24, 2015

Related Experiment Videos

Last Updated: Jun 3, 2026

Evidence for EpCAM and Cytokeratin Expressing Epithelial Cells in Normal Human and Murine Blood and Bone Marrow
08:02

Evidence for EpCAM and Cytokeratin Expressing Epithelial Cells in Normal Human and Murine Blood and Bone Marrow

Published on: April 21, 2023

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm
09:49

Holistic Facial Composite Creation and Subsequent Video Line-up Eyewitness Identification Paradigm

Published on: December 24, 2015

Area of Science:

  • Statistical science
  • Measurement theory
  • Biological research

Background:

  • Science relies on precise measurement, yet statistical evidence lacks a standardized, absolute scale.
  • Current measures like p-values and LOD scores are problematic due to inconsistent scales.
  • This issue parallels historical challenges in establishing an absolute temperature scale in physics.

Purpose of the Study:

  • To highlight the critical need for an absolute scale in statistical evidence measurement.
  • To draw parallels between measuring statistical evidence and historical temperature measurement challenges.
  • To propose a novel approach for developing an absolute evidence scale using thermodynamics.

Main Methods:

  • Measure-theoretic perspective on statistical evidence.
  • Analogy drawn between thermodynamic scales and statistical evidence scales.
  • Exploration of mathematical foundations of thermodynamics for evidence measurement.

Main Results:

  • Identified significant problems with current statistical evidence measures (p-values, LOD scores).
  • Established a formal analogy between temperature measurement and evidence measurement.
  • Laid the groundwork for applying thermodynamic principles to statistical evidence.

Conclusions:

  • The lack of an absolute scale for statistical evidence is a critical issue in modern research.
  • Thermodynamics offers a potential framework for developing a calibrated, absolute scale for evidence.
  • This approach could enhance the reliability and comparability of statistical findings across studies.