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Updated: Jun 3, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
Urine screening for Chlamydia trachomatis during pregnancy
Scott W Roberts1, Jeanne S Sheffield, Don D McIntire
1From the Department of Obstetrics and Gynecology, the University of Texas Southwestern Medical Center, Dallas, Texas.
Objective:
To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution.
Methods:
A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay.
Results:
A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]).
Conclusion:
Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.
Level Of Evidence:
II.
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