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Serpiginous choroiditis in a herpes-positive patient

Julie Rodman1, Joseph Pizzimenti

  • 1Nova Southeastern University College of Optometry, Davie, Florida, USA. rjulie@nova.edu

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|March 23, 2011
PubMed
Abstract

Insights

Herpes simplex virus may cause serpiginous choroiditis, a posterior eye condition previously considered idiopathic. Prompt laboratory testing for viral causes is crucial for effective treatment and optimal vision recovery.

Area of Science:

  • Ophthalmology
  • Virology
  • Infectious Diseases

Background:

  • Posterior segment eye infections are frequently viral.
  • Herpes simplex virus (HSV) is linked to various posterior ocular conditions.
  • Serpiginous choroiditis (SC) is often idiopathic, but viral links are emerging.

Observation:

  • A 57-year-old female presented with a 10-month history of decreased, distorted vision.
  • Funduscopy revealed peripapillary radial, grayish lesions suggestive of SC.
  • Fluorescein angiography confirmed SC; serologic testing was positive for HSV.

Findings:

  • Positive HSV serology in a patient with SC suggests a potential causative viral link.
  • This case challenges the traditional view of SC as solely idiopathic.
  • HSV infection may be an underrecognized etiology of serpiginous choroiditis.

Implications:

  • Investigating viral etiologies, particularly HSV, is essential for SC diagnosis.
  • Identifying and treating underlying viral infections can optimize patient outcomes.
  • This highlights the importance of comprehensive work-up for posterior uveitis.

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