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Published on: May 26, 2023
Internal auditory canal metastasis
A Della Puppa1, M Rossetto, F Berti
1Department of Neurosurgery, Padua University Hospital, Padua, Italy. alessandro.dellapuppa@sanita.padova.it
Abstract:
Metastasis of the inner auditory canal is a really rare event. Clinically, it usually presents with rapid worsening cranial nerve palsy. Authors present a review of the literature reporting clinical features, radiological findings, intraoperative aspects of an illustrative case. A 56-year-old female patient presented with a peripheral facial nerve palsy. MRI showed two left p-fossa tumors whose one into the inner canal. Rapid worsening of facial damage despite corticosteroid treatment and the possibility to remove both tumors in the same surgical step suggested authors to operated on the patient. Intraoperatively, inner canal tumor looked totally involving the VII-VIII nerve complex so surgical extirpation was only partially feasible. Posterior wall drilling of the meatus was performed which improved facial palsy. Leptomeningeal spinal seeding occurred and spinal irradiation was performed. The case highlights the importance of maintaining a high degree of awareness of the auditory canal metastasis in patients with a previous history of malignancy who develop a rapid progressive peripheral VII nerve palsy. Furthermore, our case and literature data suggest that inner canal metastasis is a distinct entity from temporal bone and ponto-cerebellar angle metastasis on the base of the peculiarity of clinical features, prognosis, therapeutic strategies. In fact, inner canal metastases usually arise in patients apparently cured, and they imply a better prognosis even if with an higher risk of leptomeningeal seeding. Moreover, surgery rarely allows the removal of the lesion, also if symptoms relief may be achieved, as in our case.
Insights
Inner auditory canal metastasis, a rare event, often presents as rapid cranial nerve palsy. This distinct entity offers a better prognosis but carries a higher risk of leptomeningeal seeding.
Area of Science:
- Neurology
- Oncology
- Otolaryngology
Background:
- Metastasis to the inner auditory canal (IAC) is exceptionally rare.
- Clinical presentation typically involves rapid cranial nerve palsy, particularly facial nerve involvement.
Observation:
- A 56-year-old female with a history of malignancy presented with peripheral facial nerve palsy.
- MRI revealed two posterior fossa tumors, one infiltrating the IAC, affecting the VII-VIII nerve complex.
- Despite corticosteroid treatment, facial nerve palsy rapidly worsened.
Findings:
- Surgical extirpation of the IAC tumor was only partially feasible due to extensive nerve involvement.
- Posterior wall drilling of the internal auditory canal improved facial palsy symptoms.
- Leptomeningeal spinal seeding occurred post-operatively, necessitating spinal irradiation.
Implications:
- High awareness of IAC metastasis is crucial in patients with prior malignancy and rapid progressive VII nerve palsy.
- IAC metastasis appears distinct from temporal bone and CPA metastases, with unique clinical features, prognosis, and therapeutic strategies.
- While complete surgical removal is rare, symptom relief is achievable, and IAC metastasis may portend a better prognosis despite increased leptomeningeal seeding risk.
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