Internal auditory canal metastasis

A Della Puppa1, M Rossetto, F Berti

  • 1Department of Neurosurgery, Padua University Hospital, Padua, Italy. alessandro.dellapuppa@sanita.padova.it

Insights

Inner auditory canal metastasis, a rare event, often presents as rapid cranial nerve palsy. This distinct entity offers a better prognosis but carries a higher risk of leptomeningeal seeding.

Area of Science:

  • Neurology
  • Oncology
  • Otolaryngology

Background:

  • Metastasis to the inner auditory canal (IAC) is exceptionally rare.
  • Clinical presentation typically involves rapid cranial nerve palsy, particularly facial nerve involvement.

Observation:

  • A 56-year-old female with a history of malignancy presented with peripheral facial nerve palsy.
  • MRI revealed two posterior fossa tumors, one infiltrating the IAC, affecting the VII-VIII nerve complex.
  • Despite corticosteroid treatment, facial nerve palsy rapidly worsened.

Findings:

  • Surgical extirpation of the IAC tumor was only partially feasible due to extensive nerve involvement.
  • Posterior wall drilling of the internal auditory canal improved facial palsy symptoms.
  • Leptomeningeal spinal seeding occurred post-operatively, necessitating spinal irradiation.

Implications:

  • High awareness of IAC metastasis is crucial in patients with prior malignancy and rapid progressive VII nerve palsy.
  • IAC metastasis appears distinct from temporal bone and CPA metastases, with unique clinical features, prognosis, and therapeutic strategies.
  • While complete surgical removal is rare, symptom relief is achievable, and IAC metastasis may portend a better prognosis despite increased leptomeningeal seeding risk.

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