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Updated: Jan 19, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Basal cell carcinoma miming cutaneous melanoma
Ina Ruxandra Petrescu1, Maria Sajin, Mariana Costache
1Department of Plastic Surgery and Reconstructive Microsurgery, University Emergency Hospital of Bucharest, Romania. inapetrescu@yahoo.com
Abstract:
In the last decades, the incidence of skin cancer is in continuous growth, but the mortality remains at the same level thanks to the new imaging diagnosis methods and surgical treatment. A real problem regarding differential diagnosis between cutaneous melanoma and non-melanotic skin tumor appear, despite advanced technologies, which have a major impact on treatment management. We reported two cases with clinical and dermoscopic aspects of cutaneous melanoma, sustained by positive lymphoscintigraphy. The histopathological exams established that the skin tumor was a pigmented basal cell carcinoma. In such difficult cases, the accuracy of diagnosis is certified only by the microscopical examination with clinical, treatment and prognosis changes.
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