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Peritoneum

Peritoneum

The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...

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Updated: Jun 3, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum

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[Peritoneal carcinomatosis].

I Königsrainer¹, S Beckert, T Lehmann

¹Klinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Hoppe-Seyler-Strasse 3, Tübingen, Germany.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen

|March 23, 2011

Summary

This summary is machine-generated.

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) offer a curative option for peritoneal carcinomatosis. Careful patient selection and comprehensive management are crucial for successful outcomes and quality of life.

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Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

Area of Science:

Oncology
Surgical Oncology
Gastroenterology

Context:

Cytoreductive surgery (CS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a standard curative treatment for peritoneal carcinomatosis.
Complete cytoreduction is essential for favorable prognosis, often requiring extensive surgery like multi-organ resection and parietal peritonectomy (PE).

Purpose:

To highlight the established role of CS + HIPEC in treating peritoneal carcinomatosis.
To emphasize the importance of complete cytoreduction and patient quality of life.
To discuss the complexities of managing patients undergoing PE and HIPEC.

Summary:

The combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) is an established curative therapy for gastrointestinal and gynecological peritoneal carcinomatosis.
Achieving complete cytoreduction, often necessitating multi-organ resection and parietal peritonectomy (PE), is critical for prognosis.
While morbidity is between 25-35% with low mortality (<5%) in experienced centers, comprehensive management including surgical technique, intraoperative decisions, intensive care, and pain management is vital.
Patient selection remains a significant challenge, with computed tomography and FDG-PET imaging playing key roles in assessing operability.

Impact:

Establishes CS + HIPEC as a viable curative approach for specific cancers.
Underscores the critical role of surgical expertise and multidisciplinary care in optimizing patient outcomes.
Highlights the importance of advanced imaging in patient selection for this complex procedure.