Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Heart Failure VI: Adjunct Therapies

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

Heart Failure V: Medical Management

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...

Heart Failure II: Pathophysiology

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...

Heart Failure VII: Nursing Interventions

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...

Heart Failure IV: Classification and Diagnostic Evaluation

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Cardiac implantable electronic device-related surgery as a perfect example for interdisciplinary cooperation].

Herzschrittmachertherapie & Elektrophysiologie·2025

Same author

[You can only understand today if you know yesterday : The history of rhythmology in Germany].

Herzschrittmachertherapie & Elektrophysiologie·2024

Same author

[Electrophysiology goes imaging!]

Herzschrittmachertherapie & Elektrophysiologie·2022

Same author

[Surprising mechanism of highly symptomatic tachycardia in a young patient : Diagnosis and treatment].

Herzschrittmachertherapie & Elektrophysiologie·2021

Same author

[Echocardiographic assessment of myocardial function during His bundle and right ventricular pacing].

Herzschrittmachertherapie & Elektrophysiologie·2020

Same author

[Canalopathies, arrhythmogenic right ventricular cardiomyopathy and artefacts].

Herzschrittmachertherapie & Elektrophysiologie·2019

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

[Electrical therapy for heart failure. Perspectives for 2011].

¹Klinik für Innere Medizin – Kardiologie & Angiologie, Evangelisches Krankenhaus. carsten.israel@evkb.de

Herzschrittmachertherapie & Elektrophysiologie

|March 23, 2011

Summary

Established heart failure treatments like implantable defibrillators (ICDs) and cardiac resynchronization therapy (CRT) have questions regarding optimal use. New therapies modulating calcium handling and autonomic balance are emerging, with some showing initial promise in trials.

More Related Videos

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Published on: June 30, 2023

Related Experiment Videos

Last Updated: Jun 3, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Clinical Application of Phase Angle and BIVA Z-Score Analyses in Patients Admitted to an Emergency Department with Acute Heart Failure

Published on: June 30, 2023

Area of Science:

Cardiology
Biomedical Engineering
Clinical Electrophysiology

Context:

Implantable defibrillators (ICDs) and cardiac resynchronization therapy (CRT) are standard heart failure treatments.
Optimal patient selection, imaging, and pacing sites for ICDs/CRT require further clarification for daily practice.

Purpose:

To review established and emerging therapies for heart failure management.
To highlight ongoing research into novel approaches for heart failure treatment.

Summary:

Established therapies like ICDs and CRT have proven effective but present practical challenges.
Emerging treatments focus on cellular calcium handling and autonomic balance, including cardiac contractility modulation and vagal nerve stimulation.
Novel approaches such as sympathetic ganglion stimulation and multisite left ventricular pacing are under investigation.

Impact:

Provides an overview of current and future directions in heart failure device therapy.
Identifies key areas for research and clinical trial focus in optimizing heart failure management.
Informs clinicians and researchers about the evolving landscape of advanced heart failure treatments.