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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Related Experiment Video

Updated: Jun 3, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

[Ocular ischemic syndrome].

A Pielen1, B Junker, L Goldammer

  • 1Universitäts-Augenklinik Freiburg, Killianstr. 5, 79106 Freiburg. amelie.pielen@uniklinik-freiburg.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|March 23, 2011
PubMed
Summary
This summary is machine-generated.

Ocular ischemic syndrome (OIS) is a rare condition caused by blocked arteries, leading to vision loss and pain. Early medical and neurological exams are crucial for managing this high-mortality disease.

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Area of Science:

  • Ophthalmology
  • Vascular Medicine
  • Neurology

Context:

  • Ocular ischemic syndrome (OIS) is a severe condition resulting from chronic artery occlusion, often affecting the internal carotid artery.
  • Patients typically experience significant visual loss and ocular pain.
  • OIS is rare and can be misdiagnosed, often confused with diabetic retinopathy or central retinal vein occlusion.

Purpose:

  • To review the clinical findings associated with OIS.
  • To outline the diagnostic approaches for OIS.
  • To discuss therapeutic strategies for managing neovascular complications in OIS.

Summary:

  • OIS presents with visual loss and pain due to arterial blockage, primarily the internal carotid artery.
  • Differential diagnosis is critical, distinguishing OIS from conditions like diabetic retinopathy.
  • Management focuses on treating neovascular complications, with mandatory medical and neurological evaluations due to high patient mortality.

Impact:

  • Highlights the importance of comprehensive medical and neurological assessments in OIS patients.
  • Emphasizes timely diagnosis and treatment of neovascular complications to improve patient outcomes.
  • Contributes to understanding and managing this rare but serious ocular vascular disease.