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Enzyme-labeled DNA probes

J L Woodhead1, R Fallon, H Figueiredo

  • 1Department of Biochemistry, Charing Cross and Westminster Medical School, London, UK.

Methods in Molecular Biology (Clifton, N.J.)
|March 23, 2011
PubMed

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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