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Updated: Jun 3, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Implantable cardioverter-defibrillator implementation in acute heart failure syndromes: unanswered questions
Norman C Wang1, Jonathan P Piccini, Mihai Gheorghiade
1Cardiovascular Institute, University of Pittsburgh Medical Center, 200 Lothrop Street, B-535, Pittsburgh, PA 15213, USA. wangnc@upmc.edu
Insights
Implantable cardioverter-defibrillators reduce mortality in stable heart failure patients. Their benefit in acute heart failure settings with reduced ejection fraction remains unknown, warranting further literature review.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Implantable cardioverter-defibrillators (ICDs) are effective in reducing mortality for patients with reduced left ventricular ejection fraction.
- Proven benefits are established in primary and secondary prevention for stable outpatients with heart failure.
Purpose of the Study:
- To review the existing literature on the efficacy of ICDs in patients with chronically reduced left ventricular ejection fraction in the acute heart failure setting.
Main Methods:
- Literature review of randomized trials and studies.
- Analysis of data concerning ICD implantation in acute heart failure scenarios.
Main Results:
- Existing evidence primarily focuses on stable heart failure patients.
- The benefit of ICDs in acute heart failure settings with reduced ejection fraction is not yet established.
Conclusions:
- Further research is needed to determine the role of ICDs in acute heart failure management.
- The current literature does not support or refute ICD use in this specific patient population.
Abstract:
Implantable cardioverter-defibrillators have proven efficacy in reducing mortality in patients with reduced left ventricular ejection fraction in both the primary and the secondary prevention settings. All randomized trials demonstrating this benefit have been conducted in outpatients with stable heart failure symptoms. Whether implantable cardioverter-defibrillators confer a benefit when implemented in patients with chronically reduced left ventricular ejection fraction in the acute heart failure setting is unknown. The purpose of this document is to review the existing literature related to this subject.
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