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Diagnostic studies
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[Celiac disease in Emilia Romagna].

P Cacciari1, M T Montella, P Alvisi

  • 1Dipartimento di Sanità Pubblica, Universitá degli Studi di Bologna. paolo.cacciari@unibo.it

Annali Di Igiene : Medicina Preventiva E Di Comunita
|March 24, 2011
PubMed
Summary
This summary is machine-generated.

Celiac disease prevalence is underestimated globally. This study in Emilia Romagna found 1.8 cases per 1000 people, with significant regional variation, confirming underdiagnosis worldwide.

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Area of Science:

  • Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Celiac disease prevalence is often underestimated globally.
  • Regional variations in diagnosis and reporting contribute to underestimation.
  • Understanding local prevalence is crucial for public health initiatives.

Purpose of the Study:

  • To estimate the prevalence of celiac disease in the Emilia Romagna region.
  • To compare regional data with international celiac disease prevalence rates.
  • To highlight the ongoing underestimation of celiac disease.

Main Methods:

  • Analysis of symptomatic patients within the regional health service reimbursement program in 2008.
  • Inclusion of 7811 patients in the study cohort.
  • Examination of age-specific prevalence and district-level variations.

Main Results:

  • Overall celiac disease prevalence in Emilia Romagna was 1.8 patients per 1000 citizens.
  • Prevalence showed significant variability across districts, ranging from 1:384 in Parma to 1:909 in Piacenza.
  • No significant age-related prevalence was observed, except possibly in infants aged 0-1, potentially linked to breastfeeding.

Conclusions:

  • The study confirms the underestimation of celiac disease prevalence, consistent with findings in other countries.
  • Despite diagnostic tools like serological tests and small bowel histology, underdiagnosis persists.
  • A multidisciplinary approach is recommended to enhance celiac disease awareness and investigate its pathogenesis.