Related Experiment Video
Updated: Jun 3, 2026
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Cost analysis of the Spanish renal replacement therapy programme
Guillermo Villa1, Ana Rodríguez-Carmona, Lucía Fernández-Ortiz
1Department of Health Outcomes Research, BAP Health Outcomes Research, Oviedo, Spain. guillermo@baphealth.com
Summary
Hemodialysis (HD) dominated the Spanish Renal Replacement Therapy (RRT) program costs in 2010, exceeding 70%. Increasing peritoneal dialysis (PD) patient numbers could minimize overall RRT program expenses.
Area of Science:
- Health Economics
- Nephrology
- Public Health Policy
Background:
- Analysis of the Spanish Renal Replacement Therapy (RRT) program costs for end-stage renal disease (ESRD) patients in 2010.
- Perspective of the Public Administration.
Purpose of the Study:
- To conduct a cost analysis of the Spanish RRT program in 2010.
- To evaluate costs associated with hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (Tx).
Main Methods:
- Forecasting ESRD incidence and prevalence in Spain for 2010.
- Calculating aggregate costs for each RRT modality.
- Utilizing literature review, official bulletins, and healthcare cost databases.
Main Results:
- Forecasted incidence: HD (5409), PD (822), Tx (2317). Forecasted prevalence: HD (22,582), PD (2420), Tx (24,761).
- Average annual per-patient costs varied significantly across modalities.
- Total economic impact on Public Administration: ~€1829 million, with HD accounting for the largest share (€1327 million).
Conclusions:
- Hemodialysis (HD) represented over 70% of the total RRT program costs in 2010.
- Increasing the number of incident and prevalent patients undergoing peritoneal dialysis (PD) is recommended for cost minimization.
Related Concept Videos
01:30Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
01:26Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
01:08Renal Drug Clearance: Comparison Between Renal Excretion Methods
Renal clearance is a critical parameter encompassing kidney filtration, secretion, and reabsorption processes. It is calculated using a specific equation to determine the rate at which the kidneys clear a drug.
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
01:06Renal Drug Clearance: Overview
Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
01:15Renal Drug Excretion: Overview
As primary excretory organs, the kidneys maintain homeostasis by removing waste substances from the bloodstream. They comprise over a million units called nephrons, which serve as the kidney's functional units.
A nephron consists of two primary structures: the renal corpuscle and the renal tubule. The renal corpuscle contains the glomerulus, a network of capillaries where the first step of renal excretion, glomerular filtration, occurs. Blood pressure forces water, ions, and small molecules out...
A nephron consists of two primary structures: the renal corpuscle and the renal tubule. The renal corpuscle contains the glomerulus, a network of capillaries where the first step of renal excretion, glomerular filtration, occurs. Blood pressure forces water, ions, and small molecules out...
01:25Renal Drug Excretion: Tubular Reabsorption
Tubular reabsorption, a process occurring post-glomerular filtration of drugs in the renal tubule, is a critical determinant of drug half-life. During the process of renal excretion, as the glomerular filtrate progresses to the distal convoluted tubule (DCT), drugs that are highly permeable, lipophilic, and nonionized undergo passive reabsorption from the tubular fluid into the surrounding peritubular capillaries. This reabsorption process restricts their elimination through the kidneys. This...