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Multicystic peritoneal mesothelioma in an octogenarian: diagnosis, natural history, and treatment
Charles M Psoinos1, Dina Kandil, Bilal Piperdi
1Division of Surgical Oncology, University of Massachusetts-Memorial Medical Center, Swift House, 119 Belmont Street, Worcester, MA 01605, USA.
Abstract:
Multicystic peritoneal mesothelioma (MCPM) is a rare cystic proliferation most often seen in women of reproductive age with a history of prior abdominal surgery. This is a case report of an 83-year-old woman diagnosed with MCPM during an exploratory laparotomy for presumed peritoneal carcinomatosis from colon cancer. After complete removal of all visible MCPM, the patient remains free of both colon cancer and MCPM. This article reviews the literature with regards to the pathology, natural history, risk of malignant transformation, and current options for management of MCPM, including cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Insights
Multicystic peritoneal mesothelioma (MCPM) is a rare condition typically affecting younger women. This case report details an 83-year-old woman successfully treated for MCPM, highlighting management options.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Multicystic peritoneal mesothelioma (MCPM) is a rare neoplastic proliferation.
- It predominantly affects women of reproductive age with a history of abdominal surgery.
Observation:
- An 83-year-old woman presented with suspected peritoneal carcinomatosis from colon cancer.
- MCPM was diagnosed during an exploratory laparotomy.
Findings:
- Complete surgical resection of MCPM was achieved.
- The patient remained disease-free from both colon cancer and MCPM post-surgery.
Implications:
- This case highlights MCPM in an elderly patient, challenging typical demographics.
- Effective management includes cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
- Further research into MCPM's natural history and malignant transformation risk is warranted.
