Related Experiment Video
Updated: Jun 3, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Do cardio-vascular and periodontal diseases have a close, causal relationship?
1"Carol Davila" University of Medicine and Pharmacy, Medical Clinic of Clinical Emergency Hospital Ilfov County, Bucharest, Romania. drhoriabalan@yahoo.com
Insights
Cardiovascular diseases and periodontal diseases share common risk factors and increasing prevalence. Treating periodontal disease may improve cardiovascular health, offering significant general health benefits.
Area of Science:
- Oral health
- Cardiovascular health
- Public health
Background:
- Cardiovascular diseases (CVD) and periodontal diseases (PDs) are prevalent and increasing globally.
- Shared risk factors and high prevalence suggest a potential link between CVD and PDs.
Purpose of the Study:
- To review the evidence for a possible causal relationship between periodontal diseases and cardiovascular diseases.
- To highlight the potential public health benefits of managing periodontal disease.
Main Methods:
- Literature review of studies investigating the association between periodontal diseases and cardiovascular diseases.
- Analysis of common risk factors and potential biological mechanisms linking the two conditions.
Main Results:
- Evidence suggests a potential causal link between periodontal diseases and cardiovascular diseases.
- Periodontal diseases share common risk factors with cardiovascular diseases, contributing to their association.
Conclusions:
- Effective prevention and treatment of periodontal diseases may offer significant benefits for cardiovascular health.
- Managing periodontal disease presents a potentially impactful strategy for improving overall public health, unlike many other cardiovascular risk factors.
Abstract:
Cardiovascular (CVD) and periodontal diseases (PDs) are both characterized not only by a high prevalence, but also by a constant increase. Their association could be explained by their high prevalence and by some common risk factors. This review is highlighting a possible causal relationship between the two kinds of diseases. The possible benefit in general health could be a major one, as PDs can be prevented and treated efficiently, not as many other CV risk factors.
Related Concept Videos
Coronary Artery Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease II: Pathophysiology
Cardiovascular Drugs: Classification based on Therapeutic Indications
Causality in Epidemiology
The Oral Microbiota
