Related Experiment Video

Updated: Jun 3, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Behçet disease in children

Leyla Atmaca1, Ayse Boyvat, F Nilüfer Yalçındağ

  • 1Department Ophthalmology, Ankara University Medical School, Ankara, Turkey. leylaatmaca@ttmail.com

Ocular Immunology and Inflammation
|March 25, 2011
PubMed

Insights

Behçet disease in children is rare, affecting 3.3% of patients, with ocular involvement common. Early diagnosis and multidisciplinary care are crucial for managing this childhood uveitis condition.

Area of Science:

  • Pediatrics
  • Ophthalmology
  • Rheumatology

Background:

  • Behçet disease is a rare multisystemic inflammatory disorder.
  • Childhood-onset Behçet disease requires specific diagnostic considerations.

Purpose of the Study:

  • To determine the incidence and clinical features of Behçet disease in pediatric patients.
  • To highlight the importance of considering Behçet disease in childhood uveitis.

Main Methods:

  • Retrospective chart review of 3382 Behçet disease patients from 1986-2005.
  • Analysis focused on 110 diagnosed pediatric cases.

Main Results:

  • Children constituted 3.3% of all Behçet disease patients reviewed.
  • Ocular involvement was present in 30.9% of pediatric cases, with uveitis being a common manifestation.
  • The mean age at onset was 11.6 years and at diagnosis was 14.1 years, with a female predominance (62.7%).

Conclusions:

  • Behçet disease is an important differential diagnosis for childhood uveitis, especially in endemic regions.
  • Multidisciplinary collaboration among pediatricians, rheumatologists, ophthalmologists, and dermatologists is essential for accurate diagnosis and management.
  • Prompt recognition and management can improve outcomes for children with Behçet disease.
Abstract

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Pedigree Analysis01:35

Pedigree Analysis

Overview
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...