[Clinical evaluation of 2 years of hemodiafiltration using bicarbonate]

At the end of a previous study concerning the use of different buffers for hemodiafiltration (BHDF) in both the re-infusate (40 mM/L) and dialysate (26 mM/L). Retrospective data analysis and showed BHDF to permit good acid/base balance, good clinical tolerability and satisfactory and persistent sense of well-being. From the point of view of kinetics, it is essential to evaluate carefully the acute and/or chronic effect of an alkaline blood pH during or after dial lysis, especially since the volume distribution of bicarbonate is not known.