Related Experiment Video
Updated: Jun 3, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
Published on: July 11, 2025
Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges
S J Helyar1, J Hemmer-Hansen, D Bekkevold
1Molecular Ecology and Fisheries Genetics Laboratory, School of Biological Sciences, University of Bangor, Environment Centre Wales, Gwynedd, UK. s.helyar@bangor.ac.uk
Abstract:
Recent improvements in the speed, cost and accuracy of next generation sequencing are revolutionizing the discovery of single nucleotide polymorphisms (SNPs). SNPs are increasingly being used as an addition to the molecular ecology toolkit in nonmodel organisms, but their efficient use remains challenging. Here, we discuss common issues when employing SNP markers, including the high numbers of markers typically employed, the effects of ascertainment bias and the inclusion of nonneutral loci in a marker panel. We provide a critique of considerations specifically associated with the application and population genetic analysis of SNPs in nonmodel taxa, focusing specifically on some of the most commonly applied methods.
Related Concept Videos
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Single Nucleotide Polymorphisms-SNPs
What is Population Genetics?
Analysis of Population Pharmacokinetic Data
Mutation, Gene Flow, and Genetic Drift
Gene Flow

