Breastfeeding and infant size: evidence of reverse causality

Michael S Kramer1, Erica E M Moodie, Mourad Dahhou

  • 1Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada. michael.kramer@mcgill.ca

Insights

Smaller infant size, particularly weight for age, increases the risk of weaning or stopping exclusive breastfeeding. This suggests infant growth influences feeding decisions, complicating breastfeeding research.

Area of Science:

  • Pediatrics
  • Human Nutrition
  • Public Health

Background:

  • Prolonged and exclusive breastfeeding is associated with slower infant growth in the first year.
  • Infant feeding and growth are dynamic processes influenced by bidirectional interactions.
  • Previous research may oversimplify the causal link between breastfeeding and growth due to these complex dynamics.

Purpose of the Study:

  • To investigate the influence of infant size on subsequent infant feeding decisions.
  • To assess whether smaller infant size predicts weaning or discontinuation of exclusive breastfeeding.
  • To explore the dynamic relationship between infant growth and feeding patterns.

Main Methods:

  • Observational analysis of 17,046 Belarusian infants from a cluster-randomized trial.
  • Analysis restricted to breastfed infants at the start of follow-up intervals.
  • Examined associations between infant size (weight/length) and subsequent weaning or cessation of exclusive breastfeeding.

Main Results:

  • Smaller infant size, especially weight-for-age, was significantly associated with increased risk of weaning (aOR=1.2-1.6).
  • Smaller size also significantly increased the risk of discontinuing exclusive breastfeeding (aOR=1.2-1.6).
  • These associations were most pronounced between 2 and 6 months of age.

Conclusions:

  • Infant size, particularly smaller size, appears to influence decisions regarding breastfeeding duration and exclusivity.
  • Dynamic processes, including infant size influencing feeding, complicate causal inferences about breastfeeding's effect on growth.
  • Further research is needed to disentangle the complex interplay between infant growth and feeding behaviors.

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