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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Skin Diseases and Disorders

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Defense Against Bacterial Pathogens

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Phagocytes
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Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

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Gastritis II: Pathophysiology

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Regulation of Bacterial Virulence

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Related Experiment Video

Updated: Jun 3, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

PYODERMA VEGETANS WITH lg A DEFICIENCY.

Sandeep Kumar1, Zac Boyce, Catherine McKay

  • 1Royal Brisbane Hospital, Brisbane.

Indian Journal of Dermatology
|March 25, 2011
PubMed
Summary
This summary is machine-generated.

A man with immunoglobulin A (IgA) deficiency developed pyoderma vegetans. Topical treatment with aluminium subacetate effectively resolved the skin condition.

Keywords:
IgA deficiencyPyoderma vegetansaluminium subacetate

Related Experiment Videos

Last Updated: Jun 3, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Area of Science:

  • Dermatology
  • Immunology

Background:

  • Congenital immunoglobulin A (IgA) deficiency is a primary immunodeficiency.
  • Pyoderma vegetans is a rare, chronic bacterial skin infection characterized by pustules and vegetating plaques.

Purpose of the Study:

  • To report a case of pyoderma vegetans in a patient with congenital IgA deficiency.
  • To highlight the efficacy of topical aluminium subacetate in treating this condition.

Main Methods:

  • Case report of a 41-year-old male patient.
  • Clinical observation and treatment response assessment.

Main Results:

  • The patient presented with pyoderma vegetans during a subtropical vacation.
  • Symptoms resolved effectively with topical aluminium subacetate treatment.

Conclusions:

  • Pyoderma vegetans can occur in individuals with IgA deficiency.
  • Topical aluminium subacetate is a viable treatment option for pyoderma vegetans.