Related Experiment Video
Updated: Jun 3, 2026
![[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Oxidative photoredox catalysis: mild and selective deprotection of PMB ethers mediated by visible light
Joseph W Tucker1, Jagan M R Narayanam, Pinkey S Shah
1Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, 590 Commonwealth Ave., Boston, MA, USA.
Abstract:
Herein we report an advancement in the application of visible light photoredox catalysts in the oxidation of electron-rich arenes resulting in the selective deprotection of para-methoxybenzyl (PMB) ethers. This method is highlighted by excellent functional group tolerance, protecting group orthogonality, mild reaction conditions and avoidance of stoichiometric redox byproducts.
Related Concept Videos
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Regioselectivity of Electrophilic Additions-Peroxide Effect
Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation
The carbonyl center is activated by...
Cycloaddition Reactions: MO Requirements for Photochemical Activation

