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Updated: Jun 3, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
[Histological findings in an irradiated choroidal melanoma]
S Koinzer1, H Hasselbach, J H Bräsen
1Klinik für Ophthalmologie, UK-SH Campus Kiel, Arnold-Heller-Strasse 3, Kiel, Germany. koinzer@auge.uni-kiel.de
Background:
Histological findings of choroidal melanomas after proton beam irradiation have been reported for complicated cases after enucleation. We present specimens of a tumor after transretinal probe excision.
Patient And Methods:
One year after irradiation, the biopsy was examined histologically.
Results:
The specimens showed pigmented, spindle-shaped cells staining positively for Melan-A and HMB-45. Ki-67 showed low proliferation. Caspase-3 staining was normal.
Conclusions:
The melanoma still contained vital and even single proliferating cells, but regressed afterwards without additional therapy.
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