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Updated: Jun 3, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
A modified technique for insertion of dual lumen bicaval cannulae for venovenous extracorporeal membrane oxygenation
Richard H Trimlett1, Jeremy J Cordingley, Mark J Griffiths
1Department of Cardiac Surgery, Royal Brompton Hospital, Sydney Street, London, United Kingdom.
Purpose:
Venovenous extracorporeal membrane oxygenation is used increasingly in adults with severe acute reversible respiratory failure. Cannulation is associated with a risk of vascular damage or cardiac perforation.
Methods And Results:
This report describes a modified technique of insertion for dual lumen bicaval cannulae. We have adopted the technique on 25 occasions and had no incidence of vascular damage or cardiac perforation.
Conclusion:
We suggest that the technique may mitigate the risk of guidewire looping during insertion of the dilators/cannula and thereby reduce the risk of perforation of the right ventricle.