Related Experiment Video
Updated: Jun 3, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Relationship between sense of coherence in final stage of pregnancy and postpartum stress reactions
Naomi Sekizuka1, Hiroyuki Nakamura, Keiko Shimada
1Division of Health Sciences, Graduate School of Medical Science, Kamazawa University, 6-11-80 Kodatsuno, 920-0942, Kanazawa, Ishikawa, Japan, sekky@mhs.mp.kanazawa-u.ac.jp.
Objective:
In this study, we evaluated postpartum stress using a postpartum depression scale and by measuring the level of a stress-related substance, to clarify the relationship between the stresscoping capabilities of women in the final stage of pregnancy and their postpartum stress reactions.
Methods:
Between April 2004 and October 2004, 54 women participated in a question naire survey and the measurement of their secretory immunoglobulin A (s-IgA) level as a stress-related substance two times in the final stage of their pregnancy (prepartum) and in their early puerperium (postpartum) was carried out. The questionnaire used in the prepartum stage included the following parameters: "basic features", "Sense of Coherence (SOC)" and "Japanese version of the self-assessment depression scale" of Zung. The questionnaire employed in the postpartum stage included the following parameters: "course of delivery", "Self-evaluation of delivery experience", and "Postpartum depression scale".
Results:
The depression score was higher and the s-IgA level was lower in the low-SOC score group than in the high-SOC score group, indicating that stress reactions were more intense in the low-SOC score group.
Conclusion:
It was revealed that stress reactions were more intense for women with a low SOC score. Moreover, the finding of a relationship between the low SOC score in the prepartum stage and depressive tendency suggests that women who are likely to develop depressive tendency can be predicted in the prepartum stage, and the significance of measuring SOC in the prepartum stage is thus suggested.
Related Concept Videos
Psychological Responses to Stress
Components of Stress
Interestingly, the hidden cube faces also experience these stresses, equal and opposite to those on the...
Physiological Foundation of Stress
Role of the Sympathetic Nervous System
Adrenaline triggers the...
General State of Stress
Specifically, consider a tetrahedral element where one face, labeled XYZ, is perpendicular to the line OA, and the remaining faces align with the coordinate axes with point O as the origin. At any point, such as point O, the stress tensor can be used to determine the stress...
Introduction to Stress and Lifestyle
Lazarus's Cognitive Appraisal Theory
Primary Appraisal:...

