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Updated: Jun 3, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Motivation and goal orientation in vulnerability to depression
Chrystal Vergara1, John E Roberts
1Department of Psychology, State University of New York, Buffalo, NY 14260, USA.
Abstract:
Depression may be related to motivational systems that govern approach and avoidance behaviour such as temperament and goal orientation. Using a remitted depression design we found that previously depressed and never-depressed individuals did not differ on number of approach goals generated, degree of goal commitment or extent of planning to reach goals. However, previously depressed individuals generated more avoidance goals indicating that the tendency to set avoidance goals may be a trait-like vulnerability to depression. Previously depressed individuals also reported higher activation of the behavioural approach system (BAS) raising the possibility that this system is energising approach behaviour in the service of avoiding aversive consequences.
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