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Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions

Published on: October 2, 2018

Coffee and its consumption: benefits and risks.

Masood Sadiq Butt¹, M Tauseef Sultan

¹National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan. drmsbutt@yahoo.com

Critical Reviews in Food Science and Nutrition

|March 25, 2011

Summary

This summary is machine-generated.

Coffee offers health benefits, potentially reducing risks for diabetes, neurodegenerative diseases, and certain cancers due to its rich compounds. However, excessive consumption may pose cardiovascular risks, especially for specific populations.

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Area of Science:

Nutritional Science
Pharmacology
Public Health

Background:

Coffee is a globally significant beverage with substantial economic impact.
Despite widespread consumption, debates persist regarding coffee's health benefits and risks.
Its health effects are linked to a complex phytochemistry, including caffeine and polyphenols.

Purpose of the Study:

To review the current scientific evidence on the health benefits of coffee consumption.
To critically examine the potential risks and adverse effects associated with coffee intake.
To provide a balanced perspective for scientists, stakeholders, and the general readership.

Main Methods:

Literature review of epidemiological studies and meta-analyses.
Analysis of research on coffee's phytochemical composition and mechanisms of action.
Synthesis of evidence regarding both protective and detrimental health outcomes.

Main Results:

Coffee consumption shows inverse correlations with diabetes mellitus, Parkinson's, Alzheimer's, and some cancers.
Phytochemicals like caffeine and chlorogenic acid contribute to antioxidant effects and cognitive function.
Potential risks include elevated cholesterol and cardiovascular issues from lipid components (cafestol, kahweol), and caffeine withdrawal symptoms.

Conclusions:

Coffee possesses significant health-promoting properties attributed to its bioactive compounds.
Moderate consumption may offer protection against several chronic diseases.
Excessive intake, particularly by vulnerable groups like pregnant women, warrants caution due to potential adverse cardiovascular and hormonal effects.