Related Experiment Video
Updated: Jun 3, 2026
09:45
On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
Published on: March 17, 2023
A lipase-responsive vehicle using amphipathic polymer synthesized with the lipase as catalyst
Jun Ge1, Diannan Lu, Cheng Yang
1Department of Chemical Engineering, The State Key Lab of Chemical Engineering, Tsinghua University, Beijing 100084, China.
Macromolecular Rapid Communications
|March 25, 2011
Abstract:
We describe an enzyme-responsive polymeric vehicle, which is of great interest in controlled drug delivery, biosensing, and other related areas. The polymer synthesized using lipase as catalyst in DMSO has a favorable molecular structure that is quickly hydrolyzed by lipase in aqueous phase, and allows a fast release of encapsulated molecules.
Related Concept Videos
01:24Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
01:06Lipid Digestion
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.