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Updated: Jun 3, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
[Confocal laser endomicroscopy in diagnostics of Barrett's esophagus]
Abstract:
Barrett's esophagus (BE) is known as a precursor of esophageal carcinoma, which can be defined by the presence of specialized columnar epithelium with goblet cells. Histological evaluation of biopsy specimens is time-consuming. Moreover specialized columnar epithelium is often present in a mosaic insertion within columnar-lined lower esophagus and can be missed by random biopsies. Probe-based confocal laser endomicroscopy (pCLE) allows in vivo visualization of mucosal structure and rapid diagnosis during conventional endoscopy.
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