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Updated: Jun 3, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
Published on: November 10, 2023
Non-invasive continuous positive airway pressure in monolateral lung transplant patient with pneumonia and IPF
S Aliberti1, M C Andrisani, P Tarsia
1Dipartimento toraco-polmonare e cardio-circolatorio, University of Milan, IRCCS Fondazione Po.Ma.Re, Milan, Italy. stefano.aliberti@policlinico.mi.it
Abstract:
Patients who undergo lung transplantation are prone to develop lower respiratory tract infections, leading to severe acute respiratory failure (ARF). Endotracheal intubation may not be indicated in these patients in light of a higher rate of mortality due to infections. The application of non-invasive ventilation could play a role in bridging these patients through the episode of ARF waiting for medical treatment to have effect. We report the evidence of morphological and physiological effects of the application of non-invasive continuous positive airway pressure during ARF sustained by pneumonia in a patient who underwent left lung transplantation because of idiopathic pulmonary fibrosis (IPF). We studied the effects of the application of positive end-expiratory pressure on both the right native lung affected by IPF and the transplanted lung affected by pneumonia.
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