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Published on: March 9, 2018

Complications of allergic fungal sinusitis

Sarah Bozeman1, Richard deShazo, Scott Stringer

  • 1Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.

The American Journal of Medicine
|March 26, 2011
PubMed
Abstract

Insights

Allergic fungal sinusitis can cause serious complications like vision loss and brain clots. Early identification through symptoms such as headaches and bony erosion is crucial for managing this fungal sinusitis.

Area of Science:

  • Otolaryngology
  • Allergy and Immunology
  • Infectious Diseases

Background:

  • Allergic fungal sinusitis involves eosinophil-rich mucin accumulation in paranasal sinuses.
  • This can lead to expansile masses with poorly understood complications.

Purpose of the Study:

  • To characterize and classify the complications of allergic fungal sinusitis.
  • To identify key indicators for early diagnosis.

Main Methods:

  • Included patients meeting diagnostic criteria for allergic fungal sinusitis with significant complications.
  • A cohort of 4 patients combined with 30 from literature review.

Main Results:

  • Common comorbidities include asthma and allergic rhinitis; 37% had prior nasal polyps.
  • Complications categorized as ophthalmic (13), sinobronchial (9), bony erosion (8), venous thrombosis (3), and otic (1).
  • 27% had no prior history of rhinosinusitis or nasal polyposis.

Conclusions:

  • Visual symptoms, proptosis, headaches, and bony erosion suggest allergic fungal sinusitis complications.
  • Complications can be the initial presentation of the disease.
  • Categorizing complications aids in surveillance and early detection.

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