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Related Experiment Video

Updated: Jun 3, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

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Published on: July 10, 2012

Endobronchial valve migration.

Melanie Jenkins1, Paul Vaughan, David Place

  • 1Department of Thoracic Surgery, University Hospital of Wales, Heath Park, Cardiff, CF14 4XW, UK. melaniejenkins76@hotmail.com

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|March 26, 2011
PubMed
Summary

Endobronchial valves effectively treated a persistent air leak post-surgery for severe emphysema. However, valve migration occurred, leading to recurrent chest infections, highlighting potential complications.

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Published on: November 10, 2023

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Medical Devices

Background:

  • Endobronchial valves (EBVs) offer a less invasive alternative to lung volume reduction surgery for severe emphysema.
  • EBVs are also utilized for managing persistent pulmonary air leaks and bronchopleural fistulae.

Observation:

  • A 61-year-old male with severe bullous emphysema underwent video-assisted thoracoscopic surgery and giant bullectomy.
  • The patient developed a persistent air leak post-surgery, which was immediately resolved after the insertion of two EBVs.

Findings:

  • The inserted endobronchial valves migrated within 5 months to the basal segments of the lower lobes.
  • The patient experienced recurrent chest infections following the EBV insertion and migration.

Implications:

  • This case highlights the potential risk of endobronchial valve migration after treatment for persistent air leaks.
  • Recurrent chest infections are a significant complication associated with migrated endobronchial valves.
  • Further research is needed to improve the stability and reduce complications associated with endobronchial valve therapy.