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Published on: June 8, 2017
[Lymphocytic meningitis in Bamako, Mali]
D K Minta1, M Dembele, A S Kaya
1Faculté de Médecine de Pharmacie et d’Odonto-Stomatologie, Université de Bamako, Mali. minta_daouda@yahoo.fr
Le Mali Medical
|March 26, 2011
Summary
This study highlights that HIV infection is a primary cause of lymphocytic meningitis in Bamako, with a high fatality rate. Despite challenges in diagnosis, understanding these causes is crucial for patient outcomes.
Area of Science:
- Neurology
- Infectious Diseases
- Epidemiology
Context:
- Prospective survey conducted from January 2001 to March 2002 at the Hospital of Point G in Bamako.
- Focus on the etiologic, clinical, and prognostic aspects of lymphocytic meningitis.
- Included 35 patients, with a male predominance (71.4%) and a median age of 35 years.
Purpose:
- To investigate the causes, clinical features, and outcomes of lymphocytic meningitis.
- To identify the prevalence of HIV and other infectious agents in lymphocytic meningitis cases.
- To analyze the impact of HIV co-morbidity on lethality.
Summary:
- HIV serology was positive in 83.9% of patients.
- Common clinical presentations included encephalitis (15 cases) and meningoencephalitis (12 cases).
- Cerebrospinal fluid analysis identified Cryptococcus neoformans in 9 cases; etiology remained unknown in 10 cases.
- HIV infection was the principal cause of lymphocytic meningitis, associated with a 75% lethality rate, though not statistically different from HIV-negative patients.
Impact:
- Highlights the significant burden of lymphocytic meningitis, particularly in the context of HIV co-morbidity.
- Underscores diagnostic challenges and the need for improved etiological determination in resource-limited settings.
- Provides critical data for understanding and managing lymphocytic meningitis in Bamako, Mali.
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