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Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...

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High-throughput screening: speeding up porous materials discovery.

Philipp Wollmann1, Matthias Leistner, Ulrich Stoeck

  • 1Dresden University of Technology, Department of Inorganic Chemistry, Bergstr. 66, 01069 Dresden, Germany.

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A novel Infrasorb-12 tool rapidly screens material porosity with high accuracy. This innovation aids in discovering new cobalt-based metal-organic frameworks for advanced applications.

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Area of Science:

  • Materials Science
  • Chemistry

Background:

  • Screening material porosity is crucial for applications like catalysis and gas storage.
  • Existing methods for porosity assessment can be time-consuming and less accurate.

Purpose of the Study:

  • To introduce a new tool, Infrasorb-12, for efficient porosity screening.
  • To demonstrate the tool's capability in identifying high surface area materials rapidly and accurately.
  • To showcase its application in the discovery of novel cobalt-based metal-organic frameworks.

Main Methods:

  • Development and application of the Infrasorb-12 tool for material analysis.
  • High-throughput screening of potential candidates for high surface area.
  • Characterization of newly discovered cobalt-based metal-organic frameworks.

Main Results:

  • The Infrasorb-12 tool enables rapid and accurate identification of materials with high surface area.
  • Successful application in discovering new cobalt-based metal-organic frameworks.
  • Demonstrated efficiency in accelerating materials discovery.

Conclusions:

  • Infrasorb-12 is an effective tool for high-throughput porosity screening.
  • The tool significantly reduces the time and effort required for identifying promising materials.
  • Facilitates the discovery of advanced materials like cobalt-based metal-organic frameworks.