Do you know this syndrome? Becker nevus syndrome
Denise Steiner1, Fernanda Ayres de Morais e Silva, André César Antiori Freire Pessanha
1University of Mogi das Cruzes, Sao Paulo, SP, Brazil.
Anais Brasileiros De Dermatologia
|March 26, 2011
Summary
Becker nevus syndrome links Becker's nevus with breast hypoplasia and ipsilateral bone/muscle changes. This hormone-dependent disorder involves androgen receptor activity, influencing lesion development.
Area of Science:
- Endocrinology
- Dermatology
- Genetics
Background:
- Becker nevus syndrome is characterized by the association of Becker's nevus with ipsilateral breast hypoplasia and skeletal or muscular abnormalities.
- It is hypothesized to be a hormone-dependent condition influenced by androgen receptor activity.
Observation:
- This report details a unique case of Becker nevus syndrome.
- The case presents with rare systematization of lesions and significant extracutaneous manifestations.
Findings:
- The underlying mechanism is thought to involve increased androgen receptor activity in Becker's nevus.
- This hormonal disturbance may play a role in the development of associated congenital anomalies.
Implications:
- This case highlights the diverse clinical spectrum of Becker nevus syndrome.
- Understanding the role of androgen receptors may offer insights into managing associated conditions.
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