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Related Concept Videos

Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...

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Knee Arthrocentesis in Adults
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Published on: February 25, 2022

Urethritis due to Corynebacterium glucuronolyticum.

Fátima Galan-Sanchez1, Pilar Aznar-Marin, Pilar Marin-Casanova

  • 1Clinical Microbiology Laboratory, Puerta del Mar University Hospital, Avda. Ana de Viya 21, 11009 Cádiz, Spain.

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|March 26, 2011
PubMed
Summary

Corynebacterium glucuronolyticum, a cause of non-gonococcal urethritis, requires accurate diagnosis and treatment to prevent complications like prostatitis. Prompt identification and antimicrobial susceptibility testing are crucial for effective management.

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Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
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Published on: December 4, 2020

Area of Science:

  • Urology
  • Microbiology
  • Infectious Diseases

Background:

  • Urethritis is a common condition, often caused by sexually transmitted infections.
  • Non-gonococcal urethritis (NGU) can have various bacterial etiologies.
  • Corynebacterium species, including Corynebacterium glucuronolyticum (synonym: Corynebacterium seminale), are increasingly recognized as potential pathogens in urogenital infections.

Observation:

  • A case of urethritis in a young male patient is presented.
  • The causative agent was identified as Corynebacterium glucuronolyticum.
  • This bacterium is not considered normal urogenital flora in symptomatic individuals.

Findings:

  • Accurate diagnosis of Corynebacterium glucuronolyticum is essential for appropriate management.
  • Antimicrobial susceptibility testing is recommended to guide treatment and address potential resistance.
  • The patient in this case was successfully treated with fluoroquinolones, achieving symptom resolution within two weeks.

Implications:

  • Timely and accurate diagnosis of NGU caused by Corynebacterium glucuronolyticum can prevent complications such as prostatitis.
  • Understanding the role of Corynebacterium seminale in urethritis aids in developing targeted treatment strategies.
  • This case highlights the importance of considering less common pathogens in the differential diagnosis of urethritis.