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Updated: Jun 3, 2026
Purification, Expansion, and Flow Cytometry-Based Phenotyping of Mouse Derived Bone Marrow Mesenchymal Stem Cells
Published on: July 11, 2025
The purification of mouse hematopoietic stem cells at sequential stages of maturation
1Departments of Internal Medicine and Cell and Developmental Biology, Howard Hughes Medical Institute and University of Michigan, Ann Arbor, MI.
Hematopoietic stem cells (HSCs) are rare, self-renewing progenitors that give rise to all lineages of blood cells. HSCs can be found in all hematopoietic organs, from the para-aortic mesoderm (1),(2) and yolk sac (3),(4) in fetuses to the bone marrow (reviewed in ref. 5), blood and spleens of adults.
Hematopoietic stem cells (HSCs) are rare, self-renewing progenitors that give rise to all lineages of blood cells. HSCs can be found in all hematopoietic organs, from the para-aortic mesoderm (1),(2) and yolk sac (3),(4) in fetuses to the bone marrow (reviewed in ref. 5), blood and spleens of adults.
