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Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Borderline Personality Disorder01:25

Borderline Personality Disorder

Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...

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Updated: Jun 3, 2026

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
08:29

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

Pathways to suicidal behavior in posttraumatic stress disorder.

Maria Panagioti1, Patricia A Gooding, Graham Dunn

  • 1School of Psychological Sciences, University of Manchester, Oxford.

Journal of Traumatic Stress
|March 26, 2011
PubMed
Summary
This summary is machine-generated.

Suicidal behavior in posttraumatic stress disorder (PTSD) is linked to life impairment and depressive symptoms. Addressing these factors may help reduce suicide risk in individuals with PTSD.

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Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
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Last Updated: Jun 3, 2026

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
08:29

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes
05:03

Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes

Published on: December 15, 2023

Area of Science:

  • Psychology
  • Psychiatry
  • Mental Health Research

Background:

  • Chronic posttraumatic stress disorder (PTSD) is a significant mental health condition.
  • Suicidal behavior is a serious concern among individuals with PTSD.

Purpose of the Study:

  • To investigate the pathways leading to suicidal behavior in civilian adults with chronic PTSD.
  • To develop a statistical model illustrating the relationships between PTSD, functional impairment, depressive symptoms, and suicidal behavior.

Main Methods:

  • Utilized statistical modeling programs TETRAD II and Mplus.
  • Analyzed data from 94 civilian participants diagnosed with chronic PTSD.
  • Identified direct and indirect associations between various factors and suicidal behavior.

Main Results:

  • Two primary paths to suicidal behavior were identified in PTSD.
  • Path 1: Suicidal behavior directly linked to life impairment, affecting occupational and social functioning.
  • Path 2: Suicidal behavior directly linked to depressive symptoms, associated with PTSD severity.

Conclusions:

  • Negative perceptions of functional impairment and depression are strongly associated with suicidal behavior in PTSD.
  • Findings suggest potential targets for intervention to mitigate suicide risk in PTSD populations.
  • Factors such as medication, employment, and perceived threat to life also influence the model.