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Prevention of peritoneal dialysis-related infections

Sharon J Nessim1

  • 1Department of Medicine, Division of Nephrology, Jewish General Hospital, Montreal, Quebec, Canada. sharon.nessim@mcgill.ca

Seminars in Nephrology
|March 29, 2011
PubMed

Insights

Peritoneal dialysis (PD) infections cause significant patient morbidity and technique failure. This review details PD infection microbiology and discusses strategies to reduce PD-related infections, including antibiotic use and catheter techniques.

Area of Science:

  • Nephrology
  • Infectious Diseases

Background:

  • Peritoneal dialysis (PD) is a vital renal replacement therapy.
  • PD-related infections, including peritonitis and catheter site infections, are major complications.
  • These infections lead to increased morbidity, mortality, and technique failure.

Purpose of the Study:

  • To review the microbiology and outcomes of PD-related infections.
  • To discuss various strategies for reducing the incidence of PD infections.

Main Methods:

  • Literature review focusing on PD-related infections.
  • Analysis of microbiological data and clinical outcomes.
  • Synthesis of evidence on infection prevention strategies.

Main Results:

  • PD peritonitis and catheter infections have distinct microbiological profiles.
  • Several interventions show promise in reducing infection risk.
  • Key strategies include antibiotic prophylaxis, optimized catheter design and insertion, patient education, and advanced connectology.

Conclusions:

  • Effective management of PD-related infections requires a multifaceted approach.
  • Implementing evidence-based strategies can significantly decrease infection rates.
  • Reducing PD infections is crucial for improving patient outcomes and long-term technique survival.

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