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Cardiac surgery in Down syndrome.

A Sheehan1, O C Ward, D F Duff

  • 1Department of Cardiology, Our Lady's Hospital for Sick Children, Dublin.

Irish Medical Journal
|June 1, 1990
PubMed
Summary
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This study analyzed cardiac surgery outcomes for 42 children with Down syndrome and congenital heart disease between 1976-1987. A conservative surgical approach was adopted, resulting in a 6.6% overall mortality rate.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Down Syndrome Research

Background:

  • Down syndrome is frequently associated with congenital heart defects.
  • Surgical management of these complex conditions presents unique challenges.
  • Previous outcomes data for this specific population were limited.

Purpose of the Study:

  • To evaluate the outcomes of cardiac surgery in children with Down syndrome and congenital heart disease.
  • To assess the mortality and morbidity associated with different surgical procedures.
  • To inform surgical decision-making and patient management strategies.

Main Methods:

  • Retrospective review of 42 pediatric patients with Down syndrome and congenital heart disease undergoing cardiac surgery between 1976 and 1987.

Related Experiment Videos

  • Analysis of operative procedures, including repair of patent ductus arteriosus and atrioventricular canal defects.
  • Calculation of operative mortality rates for specific procedures and the overall series.

    • Main Results:

    • The most common procedure was patent ductus arteriosus repair.
    • Four patients (9.5%) died post-operatively.
    • Overall mortality was 6.6%, with higher rates for complex repairs like complete atrioventricular canal defects.

    Conclusions:

    • A conservative surgical approach was adopted due to factors including life expectancy and lesion complexity in Down syndrome.
    • Cardiac surgery in this cohort demonstrated a manageable mortality rate, particularly with less complex procedures.
    • Findings support individualized, risk-stratified surgical management for children with Down syndrome and congenital heart disease.