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Spinal Nerves: Plexus I

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Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
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Clinical Manifestations:

Pneumothorax-I

Pneumothorax-I

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Updated: Jun 3, 2026

Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice

Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice

Published on: February 22, 2018

Intrathoracic phrenic nerve neurofibroma.

Mohamed Smahi¹, Marouane Lakranbi, Yassine Ouadnouni

¹Department of Thoracic Surgery, University Hospital Hassan II-Fez, Morocco.

The Annals of Thoracic Surgery

|March 29, 2011

Summary

This report details a rare mediastinal neurofibroma originating from the phrenic nerve. Surgical removal offers an excellent prognosis for this unusual intrathoracic tumor.

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Area of Science:

Thoracic Surgery
Surgical Pathology
Diagnostic Imaging

Background:

Intrathoracic neurogenic tumors typically present in the posterior mediastinum.
Anterior or middle mediastinal neurogenic tumors are rare and often pose diagnostic challenges.
Neurofibromas originating from the phrenic nerve are exceptionally uncommon.

Observation:

A 59-year-old woman presented with a mediastinal mass.
Radiological findings suggested a neurogenic origin.
The patient did not have von Recklinghausen disease.

Findings:

A neurofibroma was diagnosed, arising from the phrenic nerve.
Histological examination confirmed the diagnosis post-excision.
This represents the second reported case of a phrenic nerve-originating mediastinal neurofibroma.

Implications:

Accurate diagnosis of rare mediastinal tumors is crucial.
Complete surgical resection provides a favorable outcome for phrenic nerve neurofibromas.
Further research may elucidate the specific etiology of these rare presentations.