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Updated: Jun 3, 2026

A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition
Published on: July 21, 2023
Primary congenital infantile fibrosarcoma of the heart: the first confirmed case
Brian Kogon1, Bahig Shehata, Howard Katzenstein
1Department of Cardiothoracic Surgery, Emory University, Atlanta, Georgia 30322, USA. bkogon@emory.edu
Abstract:
We believe this case represents the first confirmed congenital infantile fibrosarcoma (CIFS) of the heart. We describe an infant with congenital infantile fibrosarcoma of the heart who was treated with chemotherapy and who had a life-threatening complication develop that was successfully corrected by surgery. This demonstrates an unusual presentation, remarkable imaging, and diagnostic and treatment dilemmas. More significantly, this emphasizes the importance of a multidisciplinary approach for successful treatment of congenital infantile fibrosarcoma.

