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Related Concept Videos

Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...

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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
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Published on: August 11, 2012

Trichomoniasis: evaluation to execution.

Djana F Harp1, Indrajit Chowdhury

  • 1Department of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive Southwest, Atlanta, GA, USA.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|March 29, 2011
PubMed
Summary
This summary is machine-generated.

Trichomoniasis, a common STD caused by Trichomonas vaginalis, infects millions globally. This review covers its structure, virulence, and new diagnostic and therapeutic strategies.

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Area of Science:

  • Parasitology
  • Infectious Diseases
  • Genomics

Background:

  • Trichomoniasis is the most common sexually transmitted disease (STD) worldwide.
  • Caused by the protozoan parasite Trichomonas vaginalis (T. vaginalis), it affects over 160 million people annually.
  • T. vaginalis thrives extracellularly in the human genitourinary tract, evading host defenses.

Purpose of the Study:

  • To review the structure and pathogenesis of Trichomonas vaginalis.
  • To explore parasitic virulence factors and host-pathogen interactions.
  • To summarize recent advances in the diagnosis and treatment of trichomoniasis.

Main Methods:

  • Literature review of recent developments in Trichomonas vaginalis research.
  • Analysis of genomic and proteomic data for T. vaginalis (strain G3).
  • Synthesis of information on T. vaginalis biology, virulence, and clinical management.

Main Results:

  • T. vaginalis possesses a large genome (∼160 Mb) with an extensive gene family (60,000 genes).
  • The parasite exhibits a large coding capacity in its trophozoite stage, facilitating adaptation.
  • The review consolidates current knowledge on T. vaginalis structure, pathogenicity, and therapeutic options.

Conclusions:

  • Trichomonas vaginalis is a significant global health concern due to its prevalence and complex biology.
  • Understanding T. vaginalis's unique genomic and proteomic features is crucial for developing effective interventions.
  • Advances in diagnosis and therapeutics are essential for combating this widespread STD.