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[Combined echo- and Doppler echocardiography determination of diastolic function parameters of the left ventricle]
1Zentralinstitut für Herz-Kreislauf-Forschung Akademie der Wissenschaften der DDR Berlin-Buch.
Insights
Diastolic dysfunction in hypertrophied hearts, including arterial hypertension and hypertrophic cardiomyopathy, shows reduced early diastolic filling compensated by atrial contraction. M-mode and Doppler echocardiography confirm impaired relaxation due to hypertrophy.
Area of Science:
- Cardiology
- Medical Imaging
Context:
- Arterial hypertension and hypertrophic non-obstructive cardiomyopathy can lead to left ventricular hypertrophy (LVH).
- Diastolic parameters are crucial for assessing cardiac function in these conditions.
Purpose:
- To analyze diastolic parameters using M-mode and Doppler echocardiography in patients with arterial hypertension (with and without LVH) and hypertrophic cardiomyopathy.
- To investigate the relationship between myocardial hypertrophy and diastolic filling abnormalities.
Summary:
- Doppler echocardiography revealed significantly reduced transmitral flow during rapid filling in hypertrophied hearts.
- This reduced early diastolic flow is compensated by increased atrial systole, indicated by a higher A/R quotient.
- M-mode derived isovolumetric relaxation time and retraction constant Te confirmed impaired ventricular relaxation due to myocardial hypertrophy.
Impact:
- Doppler echocardiography is effective for characterizing diastolic function in hypertrophied hearts and coronary artery disease.
- This technique can assess the efficacy of interventions like coronary artery bypass grafting and pharmacological treatments.
Abstract:
In patients with arterial hypertension with and without LVH and in hypertrophic non-obstructive cardiomyopathy diastolic parameters were analyzed with M-mode and Doppler-Echocardiography. In hypertrophied hearts we could demonstrate, that Doppler estimated transmitral flow during rapid filling phase was significantly reduced. The lower early diastolic flow is compensated by an augmentation of atrial systole (higher A/R quotient). Diastolic filling anomalies are the consequence of impaired ventricular relaxation due to myocardial hypertrophy as could been proven by the M-mode derived isovolumetric relaxation time and retraction constant Te. Doppler echo is a very good tool for characterization of diastolic function not only in hypertrophied hearts, but also in coronary artery disease. Moreover it is possible to assess the efficiency of coronary artery bypass grafting or pharmacological interventions.