Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Disorders of the Urinary System

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Anatomy of the Genitourinary System I: Kidneys and Ureters

Anatomy of the Genitourinary System I: Kidneys and Ureters

The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...

Acute Kidney Injury II: Pathophysiology

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

STSM 2025 & 2nd African Medical Writing Congress.

La Tunisie medicale·2026

Same author

Terminology focused on design and retention methods used for anterior resin-bonded fixed partial dentures in English literature: A scoping review.

Heliyon·2023

Same author

Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery.

Epilepsy research·2023

Same author

Longitudinal neurodevelopmental profile of a pediatric patient with de novo SPTAN1, epilepsy, and left hippocampal sclerosis.

Epilepsy & behavior reports·2022

Same author

Upper urinary tract urothelial carcinoma diagnosis by biopsy of a vaginal metastasis.

Urology case reports·2022

Same author

[Evaluation of management of patients under clean intermittent catheterization by general practitioners].

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2022

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

Malformative uropathies and kidney transplantation.

M Ounissi¹, T Gargah, M M Bacha

¹Department of Internal Medicine A, Charles Nicolle Hospital, Tunis, Tunisia. mejid66@yahoo.fr

Transplantation Proceedings

|March 29, 2011

Summary

Kidney transplantation outcomes for patients with malformative uropathies are comparable to other end-stage renal disease patients. These findings highlight successful kidney transplant results for uropathy-related kidney failure.

More Related Videos

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

Related Experiment Videos

Last Updated: Jun 3, 2026

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

Area of Science:

Nephrology
Urology
Transplantation Medicine

Background:

Malformative uropathies are a significant cause of end-stage renal disease (ESRD) necessitating renal replacement therapy (RRT).
Advances in medical and surgical care have improved outcomes for kidney transplantation in this patient group.

Purpose of the Study:

To describe the epidemiological profiles of patients with ESRD due to malformative uropathies who underwent kidney transplantation.
To evaluate and compare the outcomes of kidney transplantation in these patients versus those without malformative uropathies.

Main Methods:

Retrospective study of 47 kidney transplant recipients with malformative uropathies (1986-2009).
Analysis of acute rejection episodes, acute tubular necrosis, patient survival, and graft survival.
Comparison with control group using chi-square and Student t tests; survival curves analyzed with log-rank tests.

Main Results:

Malformative uropathies accounted for 9.53% of kidney transplants; vesico-ureteral reflux was the common etiology.
Lower incidence of acute tubular necrosis (8.5% vs 22.06%, P=.03) in the malformative uropathy group.
Comparable patient and graft survival rates at 1, 5, and 10 years between groups (P=NS).

Conclusions:

Kidney transplantation for malformative uropathies is becoming more common.
Outcomes, including acute rejection rates and survival, are similar to patients without malformative uropathies.
Successful kidney transplant results support transplantation as a viable option for ESRD caused by uropathies.