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Updated: Jun 3, 2026

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
Published on: May 29, 2016
Possible impact of global warming on the evolution of hemagglutinins from influenza a viruses
1National Engineering Research Center for Non-food Biorefinery, Guangxi Academy of Sciences, Nanning 530007, Guangxi, China.
Objective:
To determine if global warming has an impact on the evolution of hemagglutinins from influenza A viruses, because both global warming and influenza pandemics/epidemics threaten the world.
Methods:
4 706 hemagglutinins from influenza A viruses sampled from 1956 to 2009 were converted to a time-series to show their evolutionary process and compared with the global, northern hemisphere and southern hemisphere temperatures, to determine if their trends run in similar or opposite directions. Point-to-point comparisons between temperature and quantified hemagglutinins were performed for all species and for the major prevailing species.
Results:
The comparisons show that the trends for both hemagglutinin evolution and temperature change run in a similar direction.
Conclusion:
Global warming has a consistent and progressive impact on the hemagglutinin evolution of influenza A viruses.
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