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Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
Establishing an evidence-base for breast cancer control in developing countries
1INCTR UK, Prama House, Oxford, UK. mlodge@canet.org
Breast (Edinburgh, Scotland)
|March 29, 2011
Summary
Accessing breast cancer (BC) research from low- and middle-income countries (LMCs) is challenging. This review highlights a need for more BC prevention, early detection, and palliative care research in LMCs.
Area of Science:
- Oncology
- Public Health
- Information Science
Background:
- Breast cancer (BC) research from low- and middle-income countries (LMCs) is often inaccessible.
- A significant portion of global BC research originates from LMCs, yet its discoverability is limited.
- Existing literature reviews do not adequately capture the scope of BC research in these regions.
Purpose of the Study:
- To establish a comprehensive bibliographic database of BC research from LMCs published between 2000 and 2008.
- To analyze the landscape of BC research in LMCs, identifying key areas and research gaps.
- To assess the accessibility and indexing of BC research from LMCs in major scientific databases.
Main Methods:
- A systematic search of six bibliographic databases and cancer conference proceedings was conducted.
- Inclusion criteria focused on BC prevention, early detection, diagnosis, treatment, and palliative care in LMCs, excluding biological/genetic and animal studies.
- A total of 44,096 publications were identified, with 4,362 meeting the inclusion criteria.
Main Results:
- Only 53% of the identified publications were indexed in Medline, indicating poor accessibility.
- Research on BC treatment constituted the largest proportion (29%) of the publications.
- Mainland China was the most prolific contributor, accounting for 18% of the research, while palliative care research was minimal (2.4%).
Conclusions:
- Significant gaps exist in BC research concerning prevention, awareness, early detection, and palliative care in LMCs.
- There is a critical need for more research in these underrepresented areas within LMCs.
- Systematic reviews are essential to identify and consolidate the 'best evidence' from BC research conducted in LMCs.
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