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Emerging viral infections in rheumatic diseases
Atul A Khasnis1, Robert T Schoen, Leonard H Calabrese
1Center for Vasculitis Care and Research, Department of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, USA.
Emerging viral pathogens can cause diverse rheumatic manifestations. Rheumatologists must recognize these infections for timely diagnosis and treatment to improve patient outcomes.
Area of Science:
- Rheumatology
- Infectious Diseases
- Epidemiology
Background:
- Viral pathogens are increasingly recognized as significant contributors to rheumatic diseases.
- Understanding the evolving epidemiology of viral infections is crucial for clinical practice.
Purpose of the Study:
- To review literature on emerging viral pathogens and rheumatic diseases.
- To enhance rheumatologists' awareness for early recognition and treatment.
Main Methods:
- Literature review of case reports, series, and articles from PubMed.
- Identification of viral and human factors influencing pathogen emergence.
- Consensus-based list generation of relevant emerging viral pathogens.
Main Results:
- Changes in epidemiology and rheumatic manifestations of known viruses observed.
- New viral pathogens are emerging due to environmental and human factors.
- Hepatitis B, HIV, and Chikungunya viruses highlighted for rheumatologic relevance.
Conclusions:
- Rheumatologists must be aware of emerging viral pathogens presenting with varied rheumatologic symptoms.
- Early recognition is key for appropriate treatment and prognosis.
- Anticipate increasing numbers of emerging pathogens; ongoing research is vital.
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