Related Experiment Video
Updated: Jun 3, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
A sign to heaven: aVR lead elevation and myocardial infarction
Amir M Nia1, Natig Gassanov, Hannes Reuter
1Department of Internal Medicine III, University of Cologne, Cologne, Germany.
Insights
ST-segment elevation in the aVR lead indicates acute myocardial infarction from left main coronary artery occlusion. Recognizing this critical finding, often missed in emergency medicine training, is vital for prompt diagnosis and treatment.
Area of Science:
- Cardiology
- Emergency Medicine
- Electrocardiography
Background:
- Historically, ST-segment elevation in the aVR lead was underemphasized in emergency medicine training.
- This specific electrocardiographic finding can signify a critical left main coronary artery occlusion.
Observation:
- The case involved a myocardial infarction with proximal left anterior descending artery occlusion.
- The presenting symptom was ST-segment elevation in the aVR lead, initially misinterpreted as diffuse ischemia.
Findings:
- ST-segment elevation in the aVR lead is a crucial indicator of acute myocardial infarction, particularly when caused by left main coronary artery occlusion.
- Misinterpretation of this sign can delay life-saving interventions.
Implications:
- Increased awareness and mandatory training on recognizing aVR lead ST-segment elevation are essential for emergency department physicians.
- Prompt identification can significantly improve patient outcomes in cases of acute myocardial infarction due to coronary artery occlusion.
Abstract:
Isolated ST-segment elevation only in the aVR lead, reflecting an acute myocardial infarction due to a left main coronary artery occlusion, was ignored as part of physicians' training in emergency medicine for a long time. The recognition of aVR lead elevation is becoming more accepted as a mandatory diagnostic tool, in particular for physicians working at emergency departments. We report a typical myocardial infarction with total occlusion of the proximal part of the left anterior coronary artery, presenting with ST-segment elevation in the aVR lead, which was misinterpreted as diffuse ischemia. The lacking mandatory awareness of this entity endangered prompt and correct treatment.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin to...
Heart Failure I: Introduction
Acute Coronary Syndrome I: Introduction
Introduction Cardiac Emergencies
