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Related Experiment Video

Updated: Jun 3, 2026

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin
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[Detection of intraorbital foreign material using MDCT].

P Hoffstetter1, C Friedrich, C Framme

  • 1Institut für Röntgendiagnostik, Universitätsklinikum Regensburg. p.hoffstetter@asklepios.com

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|March 29, 2011
PubMed
Summary

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Multidetector CT (MDCT) can detect glass orbital foreign bodies, especially dense ones. Detection is reliable for glass slivers larger than 0.2 mm³ regardless of type.

Area of Science:

  • Ophthalmology
  • Radiology
  • Materials Science

Background:

  • Orbital foreign bodies pose diagnostic challenges.
  • Glass slivers are a common type of intraocular foreign body.
  • Multidetector CT (MDCT) is a key imaging modality for orbital trauma.

Purpose of the Study:

  • To evaluate the detection capabilities of MDCT for orbital glass foreign bodies.
  • To determine the minimum detectable size and density of glass slivers using MDCT.
  • To establish reliable detection thresholds for glass fragments in the orbit.

Main Methods:

  • Systematic measurement of Hounsfield Units (HU) for 20 materials, including 16 types of glass.
  • Scanning of an orbital phantom with a 16-slice MDCT using a standardized protocol.

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  • Experimental detection of sub-millimeter glass slivers with varying densities.

    • Main Results:

    • Glass exhibits high density (≥2000 HU), with refractive types reaching up to 12,400 HU.
    • Theoretically, the minimum detectable glass volume is 0.07 mm³ (at 2000 HU).
    • Experimentally, only glass slivers >8300 HU were detectable below 0.01 mm³; reliable detection occurred for volumes ≥0.2 mm³.

    Conclusions:

    • Glass orbital foreign bodies are generally detectable due to their high density.
    • Detection limits depend on glass density and size, with high-density glass detectable at 0.01 mm³.
    • MDCT reliably detects glass slivers ≥0.2 mm³ irrespective of glass type.