Related Experiment Video
Updated: Jun 3, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
[A neonate born to a mother with thyroid disease--safe or at risk?]
Małgorzata Kumorowicz-Czoch1, Jerzy Starzyk
1Klinika Endokrynologii Dzieci i Młodziezy Katedry Pediatrii, Polsko-Amerykański Instytut Pediatrii, Collegium Medium, Uniwersytet Jagielloński, Kraków.
Abstract:
The majority of thyroid diseases in pregnant women can be effectively treated and usually do not pose any risk of a fetal and neonatal thyroid dysfunctions that would be higher as compared to general population. A negative effect of a thyroid disease most commonly occurs when the condition is not properly diagnosed and treated or the mother develops an autoimmune disease. Although thyroid dysfunction in neonates associated with maternal thyroid diseases in pregnancy are not common, they may be life-threatening and associated with a risk of irreversible CNS damage. Therefore, appropriate diagnostic and management of maternal thyroid disease throughout pregnancy followed by appropriate management of a newborn is essential in the prevention of undesirable neonatal outcomes.
Related Concept Videos
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Hypothyroidism II: Pathophysiology
Hyperthyroidism II: Pathophysiology
Hyperthyroidism I: Introduction
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Teratogenicity
