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New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Interventional therapy for symptomatic-benign portal vein occlusion
Feng-Yong Liu1, Mao-Qiang Wang, Feng Duan
1Department of Interventional Radiology, Clinical Division of Internal Medicine, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Hepato-Gastroenterology
|March 30, 2011
Summary
Interventional therapy is safe and effective for symptomatic benign portal vein occlusion. Procedures like thrombolysis and angioplasty successfully treated stenosis and thrombosis, with minimal recurrence in most patients.
Area of Science:
- Interventional Radiology
- Hepatobiliary Surgery
- Vascular Medicine
Background:
- Symptomatic benign portal vein occlusion, including stenosis and thrombosis, presents a clinical challenge.
- Portal vein occlusion can arise from acute-subacute thrombosis or post-transplant anastomotic strictures.
Purpose of the Study:
- To evaluate the safety and efficacy of interventional therapy for symptomatic benign portal vein occlusion.
- To assess long-term outcomes and recurrence rates following interventional procedures.
Main Methods:
- Forty-four patients with symptomatic benign portal vein occlusion underwent interventional therapy.
- Treatments included percutaneous transhepatic portal vein branch puncture (18 patients) and transjugular intrahepatic portosystemic shunt (26 patients).
- Procedures encompassed local thrombolysis, mechanical thrombectomy, balloon dilatation, and stent placement.
Main Results:
- All interventional therapies were technically successful without serious complications.
- Post-treatment angiography showed patent portal veins with residual stenosis <20% in 34 patients and <40% in 8 patients.
- Over a 48-month follow-up, 3 patients experienced thrombus recurrence, successfully retreated; 41 patients showed no recurrence.
Conclusions:
- Interventional techniques are safe and effective for treating symptomatic benign portal vein occlusion.
- Procedures like thrombolysis, mechanical thrombectomy, balloon angioplasty, and stenting offer durable solutions.
- Interventional therapy provides a successful treatment option with a low recurrence rate for portal vein occlusion.
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